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zipper


REFERENCES

Abu-Elneel, K., Karchi, M. and Ravid, S. (1996). Dictyostelium myosin II is regulated during chemotaxis by a novel protein kinase C. J. Biol. Chem. 271: 977-84

Afshar, K., Stuart, B. and Wasserman, S. A. (2000). Functional analysis of the Drosophila Diaphanous FH protein in early embryonic * development. Development 127(9): 1887-1897. Medline abstract: 20214846

Arnon, A., et al. (1997). Calmodulin regulation of light adaptation and store-operated dark current in Drosophila photoreceptors. Proc Natl Acad Sci 94 (11): 5894-5899. Medline abstract: 97303228 Arquier, N., et al. (2001). The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal. Development 128: 2209-2220

Barrett, K., Leptin, M. and Settleman, J. (1997). The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell 91: 905-915. Medline abstract: 98088790

Barros, C. S., Phelps, C. B. and Brand, A. H. (2003). Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport. Dev. Cell 5: 829-840. Medline abstract: 14667406

Becker, K. A. and Hart, N. H. (1999). Reorganization of filamentous actin and myosin-II in zebrafish eggs correlates temporally and spatially with cortical granule exocytosis. J. Cell Sci. 112 (Pt 1): 97-110. Medline abstract: 99059807

Betschinger, J., Mechtler, K., and Knoblich, J.A. (2003). The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature 422: 326-330. Medline abstract: 12629552

Bezanilla, M., Forsburg, S. L. and Pollard, T. D. (1997). Identification of a second myosin-II in Schizosaccharomyces pombe. Mol. Biol. Cell 8(12): 2693-2705

Billuart, P., Winter, C. G., Maresh, A., Zhao, X. and Luo, L. (2001). Regulating axon branch stability. the role of p190 RhoGAP in repressing a retraction signaling pathway. Cell 107(2): 195-207. Medline abstract: 11672527

Blake, K. J., Myette, G. and Jack, J. (1999). ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeleton. Dev. Genes Evol. 209: 555-559. Medline abstract: 99432383

Bloor, J. W. and Kiehart, D. P. (2001). zipper nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation. Dev. Biol. 239(2): 215-28. Medline abstract: 11784030

Bloor, J. W. and Kiehart, D. P. (2002). Drosophila RhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis. Development 129: 3173-3183. Medline abstract: 12070092

Bonfanti, P., et al. (1992). The molecular architecture of an insect midgut brush border cytoskeleton. Eur J Cell Biol 57: 298-307

Bradley, P. L. and Andrew, D. J. (2001). ribbon encodes a novel BTB/POZ protein required for directed cell migration in Drosophila melanogaster. Development 128(15): 3001-15. Medline abstract: 11532922

Chen, T.-L. L., Kowalczyk, P. A., Ho, G. and Chisholm, R. L. (1995). Targeted disruption of the Dictyostelium myosin essential light chain gene produces cells defective in cytokinesis and morphogenesis. J. Cell Sci. 108: 3207-18

Chisholm, R. L., et al. (1988). Dictyostelium discoideum myosin: isolation and characterization of cDNAs encoding the essential light chain. Mol. Cell. Biol. 8(2): 794-801. Medline abstract: 88174722

Cramer, L. P. and Mitchison, T. J. (1995). Myosin is involved in postmitotic cell spreading. J Cell Biol 131: 179-189

Edwards, K. A., Chang, X. J. and Kiehart, D. P. (1995). Essential light chain of Drosophila nonmuscle myosin II. J. Muscle Res. Cell. Motil. 16: 491-498 Medline abstract

Edwards, K. A. and Kiehart, D. P. (1996). Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis. Development 122: 1499-1511 Medline abstract

Fanning, A. S., et al. (1995). Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms. Cell Motil Cytoskeleton 29: 29-45

Fares, H., Peifer, M. and Pringle, J. R. (1995). Localization and possible functions of Drosophila septins. Mol. Biol. Cell 6(12): 1843-1859. Medline abstract: 96164189

Foe, V. E., Field, C. M. and Odell, G. M. (2000). Microtubules and mitotic cycle phase modulate spatiotemporal distributions of F-actin and myosin II in Drosophila syncytial blastoderm embryos. Development 127: 1767-1787. Medline abstract: 20214836

Fritz, J. L. and VanBerkum, M. F. A. (2002). Regulation of rho family GTPases is required to prevent axons from crossing the midline. Dev. Bio. 252: 46-58. Medline abstract: 12453459

Goodwin, E. B., Leinwand, L. A. and Szent-Györgyi, A.. G. (1990). Regulation of Scallop myosin by mutant regulatory light chains. J. Mol. Biol 216: 85-93

Guo, S. and Kemphues, K. J. (1996). A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382: 455-458. Medline abstract: 96310865

Hacker, U. and Perrimon, N. (1998) DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes Dev. 12: 274-284. Medline abstract: 98099751

Halsell, S. R. and Kiehart, D, P. (1998). Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. Genetics 148(4):1845-1863. Medline abstract: 98240745

Halsell, S. R., Chu, B. I. and Kiehart, D. P. (2000). Genetic analysis demonstrates a direct link between Rho signaling and nonmuscle myosin function during Drosophila morphogenesis. Genetics 155: 1253-1265. Medline abstract: 20341327

Hartshorne, D. J., Ito, M. and Erdodi, F. (1998). Myosin light chain phosphatase: subunit composition, interactions and regulation. J. Muscle Res. Cell Motil. 19: 325-341. Medline abstract: 9635276

Hicks, J. L. and Williams, D. S. (1992). Distribution of the myosin I-like ninaC proteins in the Drosophila retina and ultrastructural analysis of mutant phenotypes. J Cell Sci 101 ( Pt 1): 247-54

Hime, G. R., Brill, J. A. and Fuller, M. T. (1996). Assembly of ring canals in the male germ line from structural components of the contractile ring. J. Cell Sci. 109( Pt 12): 2779-2788. Medline abstract: 97165565

Ho, G., Chen, T. L. and Chisholm, R. L. (1995). Both the amino and carboxyl termini of Dictyostelium myosin essential light chain are required for binding to myosin heavy chain. J. Biol. Chem. 270, 27977-27981

Itoh, K. and Adelstein, R. S. (1995). Neuronal cell expression of inserted isoforms of vertebrate nonmuscle myosin heavy chain II-B. J. Biol. Chem. 270: 14533-14540

Jacinto, A., et al. (2002). Dynamic analysis of actin cable function during Drosophila dorsal closure. Curr. Biol. 12: 1245-1250. Medline abstract: 12176336

Jordan, P. and Karess, R. (1997). Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosophila. J. Cell Biol. 139(7): 1805-1819. Medline abstract: 98075092

Kagami, M., Toh-e, A. and Matsui, Y. (1998). Sro7p, a Saccharomyces cerevisiae counterpart of the tumor suppressor l(2)gl protein, is related to myosins in function. Genetics 149(4): 1717-27. Medline abstract:

Kalmes, A., et al. (1996). A serine-kinase associated with the p127-l(2)gl tumour suppressor of Drosophila may regulate the binding of p127 to nonmuscle myosin II heavy chain and the attachment of p127 to the plasma membrane. Journal of Cell Science 109: 1359-1368

Karess, R. E., et al. (1991). The regulatory light chain of nonmuscle myosin is encoded for by spaghetti squash, a gene required for cytokinesis in Drosophila. Cell 65: 1177-89

Kawamoto, S. (1994). Evidence for an internal regulatory region in a human nonmuscle myosin heavy chain gene. J Biol Chem 269: 15101-10

Kellerman, K. A. and Miller, K. G. (1992). An unconventional myosin heavy chain gene from Drosophila melanogaster. J Cell Biol 119: 823-34

Kelley, C. A., et al. (1995). A Xenopus nonmuscle myosin heavy chain isoform is phosphorylated by cyclin-p34cdc2 kinase during meiosis. J Biol Chem 270: 1395-1401

Kelley, C. A., et al. (1996). Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities. J. Cell Biol. 134: 675-687 Medline abstract

Ketchum, A. S., et al (1990). Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence. Proc Natl Acad Sci 87: 6316-20

Kim, Y.-S., et al. (2002). Constitutively active myosin light chain kinase alters axon guidance decisions in Drosophila embryos. Dev. Bio. 249: 367-381. Medline abstract: 12221012

Kitayama, C., Sugimoto, A. and Yamamoto, M. (1997). Type II myosin heavy chain encoded by the myo2 gene composes the contractile ring during cytokinesis in Schizosaccharomyces pombe. J. Cell Biol. 137(6):1309-1319

Kolega, J. (1998). Cytoplasmic dynamics of myosin IIA and IIB: spatial 'sorting' of isoforms in locomoting cells. J. Cell Sci 111( Pt 15): 2085-2095. Medline abstract: 98330433

Latham, V. M., et al. (2001). A Rho-dependent signaling pathway operating through myosin localizes ß-actin mRNA in fibroblasts. Cur. Bio. 11: 1010-1016. Medline abstract: 11470405

Lippincott, J. and Li, R. (1998). Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis. J. Cell Biol. 140(2): 355-366. Medline abstract: 98106180

Manfruelli, P., et al. (1996). The tumor suppressor gene, lethal(2)giant larvae (l(2)gl), is required for cell shape change of epithelial cells during Drosophila development. Development 122: 2283-94 Medline abstract

Mansfield, S. G., et al. (1996). Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain. J. Mol. Biol. 255: 98-109 Medline abstract

Martin-Blanco, E., et al. (1998). puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev. 12: 557-570. Medline abstract: 98139524

Matsumura, F., et al. (1998). Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J. Cell Biol. 140(1): 119-129. Medline abstract: 98087597

Mermall, V. and Miller, K. G. (1995). The 95F unconventional myosin is required for proper organization of the Drosophila syncytial blastoderm. J. Cell Biol. 129: 1575-1588

Milligan, R. A. (1996). Protein-protein interactions in the rigor actomyosin complex. Proc. Natl. Acad. Sci. 93: 21-26

Mizuno, T., Tsutsui, K. and Nishida, Y. (2002). Drosophila myosin phosphatase and its role in dorsal closure. Development 129: 1215-1223. Medline abstract: 11874917

Moores, S. L., Sabry, J. H. and Spudich, J. A. (1996). Myosin dynamics in live Dictyostelium cells. Proc Natl Acad Sci 93: 443-446

Morgan, N. S., Heintzelman, M. B. and Mooseker, M. S. (1995). Characterization of myosin-IA and myosin-IB, two unconventional myosins associated with the Drosophila brush border cytoskeleton. Dev Biol 172: 51-71

Murakami, N., et al. (1995). Phospholipid binding, phosphorylation by protein kinase C, and filament assembly of the COOH terminal heavy chain fragments of nonmuscle myosin II isoforms MIIA and MIIB. Biochemistry 34: 16046-16055

Musch, A., Cohen, D. and Rodriguez-Boulan, E. (1997). Myosin II is involved in the production of constitutive transport vesicles from the TGN. J. Cell Biol. 138(2): 291-306. Medline abstract: 97375660

Ohshiro, T., et al. (2000). Role of cortical tumor-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature 408: 593-596. Medline abstract: 21003824

Olazabal, I. M., et al. (2002). Rho-kinase and Myosin-II control phagocytic cup formation during CR, but Not FcgammaR, phagocytosis. Curr. Biol. 12: 1413-1418. Medline abstract: 12194823

Patterson, B., et al. (1997). Cold-sensitive mutants G680V and G691C of Dictyostelium myosin II confer dramatically different biochemical defects. J. Biol. Chem. 272: 27612-27617

Peng, C.-Y., et al. (2000). The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts. Nature 408: 596-600. Medline abstract: 21003825

Phillips, C. L., Yamakawa, K. and Adelstein, R. S. (1995). Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies. J Muscle Res Cell Motil 16: 379-389

Piekny, A. J., et al. (2003). The Caenorhabditis elegans nonmuscle myosin genes nmy-1 and nmy-2 function as redundant components of the let-502/Rho-binding kinase and mel-11/myosin phosphatase pathway during embryonic morphogenesis. Development 130: 5695-5704. Medline abstract: 14522875

Pollenz, R. S. and Chisholm, R. L. (1991). Dictyostelium discoideum essential myosin light chain: gene structure and characterization. Cell Mot. Cytoskel. 20: 83-94

Pollenz, R. S., et al. (1992). The Dictyostelium essential light chain is required for myosin function. Cell 69: 951-62

Post, P. L., Trybus, K. M. and Taylor, D. L. (1994). A genetically engineered, protein-based optical biosensor of myosin II regulatory light chain phosphorylation. J Biol Chem 269: 12880-7

Post, P. L., DeBiasio, R. L. and Taylor, D. L. (1995). A fluorescent protein biosensor of myosin II regulatory light chain phosphorylation reports a gradient of phosphorylated myosin II in migrating cells. Mol. Biol. Cell 6: 1755-1768

Rosenblatt, J., et al. (2004). Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell 117: 361-372. Medline abstract: 15109496

Sanders, L. C., et al. (1999). Inhibition of myosin light chain kinase by p21-activated kinase. Science 283(5410): 2083-5. Medline abstract: 99192662

Shoemaker, M. O., et al. (1990). Use of DNA sequence and mutant analysis and antisense oligodeoxynucleotides to examine the molecular basis of nonmuscle myosin light chain kinase autoinhibition, calmodulin recognition, and activity. J. Cell Biol. 111: 1107-25

Shoffner, J. D. and DeLozanne, A. (1996). Sequences in the myosin II tail required for self-association. Biochem. Biophys. Res. Commun. 218: 860-4

Simerly, C., et al. (1998). Differential expression and functions of cortical Myosin IIA and IIB isotypes during meiotic maturation, fertilization, and mitosis in mouse oocytes and embryos. Mol. Biol. Cell 9(9): 2509-25

Somlyo, A. P. and Somlyo, A. V. (2000). Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J. Physiol. 522: 177-185. Medline abstract: 10639096

Springer, M. L., Patterson, B. and Spudich, J. A. (1994). Stage-specific requirement for myosin II during Dictyostelium development. Development 120: 2651-60

Strand, D., Raska, I. and Mechler, B. M. (1994a). The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton. J. Cell Biol. 127: 1345-60

Strand, D., et al. (1994b). The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain. J Cell Biol 127: 1361-1373

Strand, D., et al. (1995). A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain. Oncogene 11: 291-301

Stull, J. T., et al. (1993). Phosphorylation of myosin light chain kinase: a cellular mechanism for Ca2+ desensitization. Mol. Cell. Biochem. 127-128: 229-237

Su, Z. and Kiehart, D. P. (2001). Protein kinase C phosphorylates nonmuscle myosin-II heavy chain from Drosophila but regulation of myosin function by this enzyme is not required for viability in flies. Biochemistry 40(12): 3606-14. Medline abstract: 11297427

Swank, D. M., et al. (2001). Alternative exon-encoded regions of Drosophila Myosin heavy chain modulate ATPase rates and actin sliding velocity. J. Biol. Chem. 276: 15117-15124. Medline abstract: 11134017

Tan, C., Stronach, B. and Perrimon, N. (2003). Roles of myosin phosphatase during Drosophila development. Development 130: 671-681. Medline abstract: 12505998

Totsukawa, G., et al. (1999). Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation. J. Cell Biol. 144(4): 735-744. Medline abstract: 99156984

Trybus, K. M., Waller, G. S. and Chatman, T. A. (1994). Coupling of ATPase activity and motility in smooth muscle myosin is mediated by the regulatory light chain. J. Cell Biol. 124: 963-969

Uyeda, T. Q. P. and Spudich, J. A. (1993). A functional recombinant myosin II lacking a regulatory light chain-binding site. Science 262: 1867-70

Uyeda, T. Q., Ruppel, K. M. and Spudich, J. A. (1994). Enzymatic activities correlate with chimaeric substitutions at the actin-binding face of myosin. Nature 368: 567-9

Uyeda, T. Q., Abramson, P. D. and Spudich, J. A. (1996).The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc. Natl. Acad. Sci. 93: 4459-4464

VanBuren, P., et al. (1994). The essential light chain is required for full force production by skeletal muscle myosin. Proc. Natl. Acad. Sci. 91: 12403-7

van Leeuwen, F. N., et al. (1999). Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nat. Cell Biol. 1: 242-248. Medline abstract: 20032782

Walker, D. S., et al. (2002). A direct interaction between IP3 receptors and Myosin II regulates IP3 signaling in C. elegans. Curr. Biol. 12: 951-956

Wesche, S., Arnold, M. and Jansen, R.-P. (2003). The UCS domain protein She4p binds to myosin motor domains and is essential for class I and class V myosin function. Curr. Biol. 13: 715-724. Medline abstract: 12725728

Wheatley, S., Kulkarni, S. and Karess, R. (1995). Drosophila nonmuscle myosin II is required for rapid cytoplasmic transport during oogenesis and for axial nuclear migration in early embryos. Development 121: 1937-1946

Winter, C. G., et al. (2001). Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell 105: 81-91. Medline abstract: 11301004

Wissmann, A., et al. (1997). Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape. Genes Dev. 11: 409-422. Medline abstract: 97195483

Wissmann, A., Ingles, J. and Mains, P. E. (1999). The Caenorhabditis elegans mel-11 Myosin phosphatase regulatory subunit affects tissue contraction in the somatic gonad and the embryonic epidermis and genetically interacts with the Rac signaling pathway. Dev. Biol. 209(1): 111-127. Medline abstract: 99225436

Wong, K. C. Y., et al. (2002). Importance of a Myosin II-containing progenitor for actomyosin ring assembly in fission yeast. Cur. Bio. 12: 724-729. Medline abstract: 12007415

Xu, X. S., et al. (2001). During multicellular migration, Myosin II serves a structural role independent of its motor function. Dev. Bio. 232: 255-264. Medline abstract: 11254362

Young, P. E., Pesacreta, T. C. and Kiehart, D. P. (1991). Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development 111: 1-14

Young, P. E., Pesacreta, T. C. and Kiehart, D. C. (1991). Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development 111: 1-14

Young, P. E., et al. (1993). Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev 7: 29-41

Zang, J. H., et al. (1997). On the role of myosin-II in cytokinesis: division of Dictyostelium cells under adhesive and nonadhesive conditions. Mol. Biol. Cell 8(12): 2617-2629

Zang, J. H. and Spudich, J. A. (1998). Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain. Proc. Natl. Acad. Sci. 95(23): 13652-7. Medline abstract: 99030624

zipper : Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

date revised: 20 July 2004 

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